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Morishita Laboratory for Developing Minds

May 2018

5/28/2018

 
Congratulations to our PhD student Milo Smith for his successful defense of his thesis "Integrative bioinformatics to discover disease & chemical modulators of critical period neuroplasticity"!
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April 2018

4/27/2018

 
Congratulations to our PhD student Masato Sadahiro for winning best oral presentation award at the 10th Friedman Brain Institute Retreat!
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March 2018

3/20/2018

 
Congratulations to our PhD student Masato Sadahiro who was awarded a NRSA individual predoctoral fellowship from NIH!

Feb 2018

2/23/2018

 
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Congratulation to our MDPhD student Elisa Nabel for her successful defense of her thesis  "Development of Prefrontal Top-Down Control for Visuospatial Attention".

Nov 2017

12/8/2017

 
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Our MDPhD student Elisa Nabel was selected to give a talk titled "Developmental Milestone for Prefrontal Top-down Cognitive Control" at Mindich Child Health and Development Retreat.

July 10 2017

7/31/2017

 
Congratulations to our MDPhD student Elisa Nabel  who was awarded the Sanfurd G. Bluestein Endowed Scholarship for MDPhD student who has demonstrated outstanding achievement in research!

June 2017

6/30/2017

 
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Our PhD student Milo Smith was selected to give a talk titled "Integrative Bioinformatics Approach to Understand the Role of Plasticity in Neurodegenerative Disease" at New York Academy of Science Conference  "Neuroplasticity, Neuroregeneration, and Brain Repair".

May 27, 2017

5/27/2017

 
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Yury Garkun, PhD, receives a Career-Starter Research Grant for 2017-2018 from the Knights Templar Eye Foundation.
NEW YORK –  May 27, 2017 /Press Release/  –– 

Mount Sinai School of Medicine researcher Yury Garkun, PhD, has received a Career-Starter Research Grant for 2017-2018 from the Knights Templar Eye Foundation.

Dr. Garkun, Postdoctoral Fellow in the lab of Dr. Hirofumi Morishita MD PhD at the department of Psychiatry, Neuroscience, Ophthalmology, Friedman Brain Institute and the Mindich Child Health and Development Institute at Mount Sinai School of Medicine, was awarded the grant for his work entitled, "Removing proteolytic brake from inhibitory circuits for recovery from Amblyopia". The grant of $65,000 was given to Dr. Yarkun on May 27th.

"Our long-term goal is to identify key regulatory mechanisms of plasticity to provide therapeutic targets for Amblyopia," said Dr. Garkun. "We recently identified a novel 'molecular brake' again proteolysis which increases in adulthood to actively limit plasticity in mouse visual cortex."

A 'lazy eye' or monocular cataract early in life results in an enduring loss of visual acuity (amblyopia) reflecting aberrant circuit remodeling within the primary visual cortex. Amblyopia affects two to four percent of the human population and exhibits little recovery in adulthood. Successful therapies for Amblyopia are therefore contingent on understanding the mechanism of adult brain plasticity.

The objective of the study is to uncover molecular and circuit mechanisms of the adult plasticity normally masked by this molecular brake. The identified mechanisms will provide novel targets for multiple interventions in amblyopia.
The Knights Templar Eye Foundation supports research that can help launch the careers of clinical or basic researchers committed to the prevention and cure of potentially blinding diseases in infants and children. They support clinical or basic research on conditions that can or may eventually be treated or prevented.

May 2017

5/19/2017

 
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Congratulations to our master student Giulia Taccheri  who was awarded the 2017 Best Thesis Prize for Master of Science in Biomedical Science! 

April 2017

5/19/2017

 
Congratulations to our MDPhD student Elisa Nabel  who was awarded the best poster award at Friedman Brain Institute Neuroscience Retreat!
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