Blog Archives

Using Teeth to Reconstruct how the Brain Develops

Two Mount Sinai researchers from different backgrounds joined forces to reconstruct critical periods of brain plasticity using teeth as a biologic hard drive. Manish Arora, BDS, MPH, PhD, Director of Exposure Biology at the Lautenberg Lab and Hirofumi Morishita, MD, PhD, from the Department of Psychiatry collaborated on a concept piece, “Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity” published in Trends in Neurosciences. Also check out this short videoclip.

Nov 22nd, 2016

12/27/2016

Milo Smith, a PhD candidate in Morishita lab and Dudley lab was selected to a talk at 4th Mindich Child Health and Development Institute Retreat, where he presented his latest findings titled "Integrative analysis of disease signatures shows inflammation disrupts juvenile experience-dependent cortical plasticity" now publsihed in eNeuro.

By appliying a systematic computational screen of hundreds of diseases for their impact on neuroplasticity, we found that inflammation disrupts plasticity in mice. This work suggests that inflammation during the childhood could have unrecognized negative consequences on the neurodevelopmental trajectory. This study is the result of an interdisciplinary collaboration between the bioinformatics lab of Joel Dudley and neuroplasticity lab of Hirofumi Morishita at Mount Sinai.

Nov 14th, 2016

12/27/2016

"Silencing select brain cells triggers social deficits in mice"

Nov. 14, 2016 SpectrumNews.org (by Ann Griswold) features Morisita lab's work in collaboration with Schahram Akbarian lab presented by our graduate student Lucy Bicks at the 2016 Society for Neuroscience Annual Meeting in San Diego. In this study we investigate the link between the specific cellular deficits and social behaviors in mice. Also check out our recent review on social cognition and prefrontal cortex by Bicks et al.

Dec 27th, 2016

Using Teeth to Reconstruct how the Brain Develops

Nov 22nd, 2016

﻿Nov 14th, 2016

"Silencing select brain cells triggers social deficits in mice"

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Nov 14th, 2016