| Milo Smith, a PhD candidate in Morishita lab and Dudley lab was selected to a talk at 4th Mindich Child Health and Development Institute Retreat, where he presented his latest findings titled "Integrative analysis of disease signatures shows inflammation disrupts juvenile experience-dependent cortical plasticity" now publsihed in eNeuro. |  |  |
By appliying a systematic computational screen of hundreds of diseases for their impact on neuroplasticity, we found that inflammation disrupts plasticity in mice. This work suggests that inflammation during the childhood could have unrecognized negative consequences on the neurodevelopmental trajectory. This study is the result of an interdisciplinary collaboration between the bioinformatics lab of Joel Dudley and neuroplasticity lab of Hirofumi Morishita at Mount Sinai.
